Antibiotic utilization: is there an effect on antimicrobial resistance?

@article{Patterson2001AntibioticUI,
  title={Antibiotic utilization: is there an effect on antimicrobial resistance?},
  author={Jan E. Patterson},
  journal={Chest},
  year={2001},
  volume={119 2 Suppl},
  pages={426S-30S}
}
The antimicrobial resistance problem in hospitals continues to worsen. In particular, extended-spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-KP) and vancomycin-resistant enterococci (VRE) are significant causes of morbidity and mortality among critically ill patients. Treating infections caused by these pathogens presents therapeutic dilemmas. The association between broad-spectrum beta-lactam overutilization and selection for ESBL-KP has been appreciated for some time; several… CONTINUE READING

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