Antibiotic treatment strategies for community-acquired pneumonia in adults.

  title={Antibiotic treatment strategies for community-acquired pneumonia in adults.},
  author={Douwe F Postma and Cornelis H van Werkhoven and Leontine J. R. van Elden and Steven F. T. Thijsen and Andy Hoepelman and Jan A. J. W. Kluytmans and Wim G. Boersma and Clara J Compaijen and Eva van der Wall and Jan C M Prins and Jan Jelrik Oosterheert and Marc Bonten},
  journal={The New England journal of medicine},
  volume={372 14},
BACKGROUND The choice of empirical antibiotic treatment for patients with clinically suspected community-acquired pneumonia (CAP) who are admitted to non-intensive care unit (ICU) hospital wards is complicated by the limited availability of evidence. We compared strategies of empirical treatment (allowing deviations for medical reasons) with beta-lactam monotherapy, beta-lactam-macrolide combination therapy, or fluoroquinolone monotherapy. METHODS In a cluster-randomized, crossover trial with… CONTINUE READING


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