Antibiotic treatment disrupts bacterial communities in the colon and rectum of simian immunodeficiency virus-infected macaques.

@article{Zevin2017AntibioticTD,
  title={Antibiotic treatment disrupts bacterial communities in the colon and rectum of simian immunodeficiency virus-infected macaques.},
  author={Alexander S. Zevin and Tiffany Hensley-McBain and Charlene J Miller and Elise A. Smith and Stanley Langevin and Nichole R. Klatt},
  journal={FEMS microbiology letters},
  year={2017},
  volume={364 23}
}
Antibiotic therapies are known to disrupt gastrointestinal (GI) bacterial communities. HIV and pathogenic simian immunodeficiency virus (SIV) infections have also been associated with disrupted GI bacterial communities. We administered a combination antibiotic therapy to six SIV-infected rhesus macaques and collected colon biopsies, stool samples and rectal swabs before and after antibiotics, and evaluated the bacterial communities at each sample site using high-throughput 16S rRNA gene… CONTINUE READING
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