Antibiotic therapy for preterm premature rupture of membranes.

  title={Antibiotic therapy for preterm premature rupture of membranes.},
  author={Brian M. Mercer},
  journal={Clinical obstetrics and gynecology},
  volume={41 2},
Antibiotic treatment of the patient with preterm premature rupture of membranes remote from term significantly prolongs pregnancy and reduces amnionitis without increasing the risk of cesarean delivery. Antibiotic treatment reduces perinatal infectious morbidity including neonatal sepsis, GBS sepsis, and pneumonia. Stratified analysis of the currently available prospective trials also demonstrates a significant reduction in gestational-dependent morbidity, specifically respiratory distress and… CONTINUE READING