Antibiotic susceptibility of bacterial colonies : An assay and experiments with Staphylococcus aureus

@inproceedings{Shao2016AntibioticSO,
  title={Antibiotic susceptibility of bacterial colonies : An assay and experiments with Staphylococcus aureus},
  author={Xinxian Shao and Justin Kim and Ha Jun Jeong and Bruce R. Levin},
  year={2016}
}
A method is presented to evaluate in vitro the efficacy of antibiotics to treat bacteria growing as discrete colonies on surfaces and the contribution of the colony structure to the antibiotic susceptibility of bacteria. Using this method, we explored the relative efficacy of six bactericidal and three bacteriostatic antibiotics to inhibit the growth and kill Staphylococcus aureus colonies of different sizes, densities and ages. As measured by the reduction in viable cell density relative to… CONTINUE READING