Antibiotic retreatment of Lyme disease in patients with persistent symptoms: a biostatistical review of randomized, placebo-controlled, clinical trials.

@article{Delong2012AntibioticRO,
  title={Antibiotic retreatment of Lyme disease in patients with persistent symptoms: a biostatistical review of randomized, placebo-controlled, clinical trials.},
  author={Allison K Delong and Barbara Blossom and Elizabeth L. Maloney and Steven E Phillips},
  journal={Contemporary clinical trials},
  year={2012},
  volume={33 6},
  pages={1132-42}
}
INTRODUCTION Lyme disease (Lyme borreliosis) is caused by the tick-borne spirochete Borrelia burgdorferi. Long-term persistent illness following antibiotic treatment is not uncommon, particularly when treatment is delayed. Current treatment guidelines for persistent disease primarily rely on findings from four randomized, controlled trials (RCTs), strongly advising against retreatment. METHODS We performed a biostatistical review of all published RCTs evaluating antibiotic retreatment… CONTINUE READING
22 Citations
54 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Efficacy of a long-term antibiotic treatment in patients with a chronic Tick Associated Poly-organic Syndrome (TAPOS)

  • J Clarissou, SongA, C Bernede, GuillemotD, DinhA, F Ader
  • Med Mal Infect 2009;39:108-15
  • 2009

Similar Papers

Loading similar papers…