Antibiotic restriction does not alter endemic colonization with resistant gram-negative rods in a pediatric intensive care unit.

@article{Toltzis1998AntibioticRD,
  title={Antibiotic restriction does not alter endemic colonization with resistant gram-negative rods in a pediatric intensive care unit.},
  author={Phillip Toltzis and Tetsuri Yamashita and Lynn Vilt and Margot Keith Green and Anthony Morrissey and Sara Spinner-Block and Jeffrey L. Blumer},
  journal={Critical care medicine},
  year={1998},
  volume={26 11},
  pages={
          1893-9
        }
}
OBJECTIVE To test whether a ceftazidime restriction policy in a pediatric intensive care unit (ICU) could decrease the endemic rate of colonization with ceftazidime-resistant gram-negative bacilli. DESIGN Prospective, pre- vs. postintervention study. SETTING University hospital pediatric ICU. PATIENTS Consecutive children admitted to the pediatric ICU over a 19-mo period. INTERVENTIONS After an observation period in which antibiotic use was not controlled, ceftazidime was prohibited… CONTINUE READING
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