Antibiotic resistance of bacterial biofilms.

@article{Hiby2010AntibioticRO,
  title={Antibiotic resistance of bacterial biofilms.},
  author={N. H{\o}iby and T. Bjarnsholt and M. Givskov and S. Molin and O. Ciofu},
  journal={International journal of antimicrobial agents},
  year={2010},
  volume={35 4},
  pages={
          322-32
        }
}
A biofilm is a structured consortium of bacteria embedded in a self-produced polymer matrix consisting of polysaccharide, protein and DNA. Bacterial biofilms cause chronic infections because they show increased tolerance to antibiotics and disinfectant chemicals as well as resisting phagocytosis and other components of the body's defence system. The persistence of, for example, staphylococcal infections related to foreign bodies is due to biofilm formation. Likewise, chronic Pseudomonas… Expand
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