• DOI:10.1016/S0140-6736(01)05321-1
Corpus ID: 46125592

Antibiotic resistance of bacteria in biofilms

@article{Stewart2001AntibioticRO,
  title={Antibiotic resistance of bacteria in biofilms},
  author={P. Stewart and J. Costerton},
  journal={The Lancet},
  year={2001},
  volume={358},
  pages={135-138}
}

P. Stewart, J. Costerton

Published 2001

Biology, Medicine

The Lancet

Bacteria that adhere to implanted medical devices or damaged tissue can encase themselves in a hydrated matrix of polysaccharide and protein, and form a slimy layer known as a biofilm. Antibiotic resistance of bacteria in the biofilm mode of growth contributes to the chronicity of infections such as those associated with implanted medical devices. The mechanisms of resistance in biofilms are different from the now familiar plasmids, transposons, and mutations that confer innate resistance to… CONTINUE READING

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