Antibiotic resistance in the intensive care unit.

@article{Kollef2001AntibioticRI,
  title={Antibiotic resistance in the intensive care unit.},
  author={Marin H Kollef and Victoria J. Fraser},
  journal={Annals of internal medicine},
  year={2001},
  volume={134 4},
  pages={298-314}
}
There is a general consensus that antimicrobial resistance has emerged as an important variable related to patient outcomes and overall resource use in the intensive care unit (ICU) (1-3). Worldwide, ICUs are faced with increasingly rapid emergence and spread of antibiotic-resistant bacteria. Both antibiotic-resistant gram-negative bacilli and gram-positive bacteria are reported as important causes of hospital-acquired infections (4-8). In many circumstancesparticularly with vancomycin… CONTINUE READING

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