Antibiotic resistance in the absence of antimicrobial use: mechanisms and implications.

@article{Pallecchi2008AntibioticRI,
  title={Antibiotic resistance in the absence of antimicrobial use: mechanisms and implications.},
  author={Lucia Pallecchi and Alessandro Bartoloni and Franco Paradisi and Gian Maria Rossolini},
  journal={Expert review of anti-infective therapy},
  year={2008},
  volume={6 5},
  pages={725-32}
}
The selective pressure generated by the use of antibiotics in clinical, veterinary, husbandry and agricultural practices is considered the major factor responsible for the emergence and spread of antibiotic-resistant bacteria since the beginning of the antibiotic era. However, recent studies have consistently demonstrated that acquired resistance traits can also be found in bacteria isolated from humans and wild animals not subjected to significant antibiotic exposure and living in remote areas… CONTINUE READING

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