Antibiotic-mediated antagonism leads to a bacterial game of rock–paper–scissors in vivo

@article{Kirkup2004AntibioticmediatedAL,
  title={Antibiotic-mediated antagonism leads to a bacterial game of rock–paper–scissors in vivo},
  author={B. Kirkup and M. Riley},
  journal={Nature},
  year={2004},
  volume={428},
  pages={412-414}
}
  • B. Kirkup, M. Riley
  • Published 2004
  • Biology, Medicine
  • Nature
  • Colicins are narrow-spectrum antibiotics produced by and active against Escherichia coli and its close relatives. Colicin-producing strains cannot coexist with sensitive or resistant strains in a well-mixed culture, yet all three phenotypes are recovered in natural populations. Recent in vitro results conclude that strain diversity can be promoted by colicin production in a spatially structured, non-transitive interaction, as in the classic non-transitive model rock–paper–scissors (RPS). In the… CONTINUE READING
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    References

    SHOWING 1-10 OF 43 REFERENCES
    Structured habitats and the evolution of anticompetitor toxins in bacteria.
    • L. Chao, B. Levin
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1981
    • 497
    • PDF
    THE PHENOTYPIC AND FITNESS EFFECTS OF COLICIN RESISTANCE IN ESCHERICHIA COLI K‐12
    • 45
    • PDF