Antibiotic dosing in multiple organ dysfunction syndrome.

Abstract

Although early and appropriate antibiotic therapy remains the cornerstone of success for the treatment of septic shock, few data exist to guide antibiotic dose optimization in critically ill patients, particularly those with multiple organ dysfunction syndrome (MODS). It is well known that MODS significantly alters the patient's physiology, but the effects… (More)
DOI: 10.1378/chest.10-2371

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