Antibiotic activity of Leu-Lys rich model peptides


To develop novel antibiotic peptides useful as therapeutic drugs, short model peptides rich in Leu and Lys were designed by changing not only the net positive charge by Lys-deletion but also in the hydrophobic helix region by Leu-deletion from a peptide analogue of cecropin A (1–8)-magainin 2 (1–12) (CA-MA) known as P5. In particular, one peptide (P6… (More)
DOI: 10.1023/A:1024995105208


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@article{Park2003AntibioticAO, title={Antibiotic activity of Leu-Lys rich model peptides}, author={Yoonkyung Park and Dong Gun Lee and Kyung-soo Hahm}, journal={Biotechnology Letters}, year={2003}, volume={25}, pages={1305-1310} }