Antibacterial properties of breast milk: Requirements for surface phagocytosis and chemiluminescence

  title={Antibacterial properties of breast milk: Requirements for surface phagocytosis and chemiluminescence},
  author={Vicky M. Avery and D. L. Gordon},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  • V. M. AveryD. L. Gordon
  • Published 1 December 1991
  • Biology, Medicine
  • European Journal of Clinical Microbiology and Infectious Diseases
The opsonic components of breast milk responsible for phagocytosis of surface-adherentStaphylococcus aureus by human polymorphonuclear leukocytes were investigated. There was significantly greater phagocytosis of bacteria pre-opsonized with 100 % breast milk than of unopsonized bacteria (p<0.001). Heat inactivation of breast milk had no effect on surface phagocytosis, indicating that phagocytosis is independent of complement. The predominant immunoglobulin in breast milk, secretory… 

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IgA- and secretory IgA-opsonized S. aureus induce a respiratory burst and phagocytosis by polymorphonuclear leucocytes.

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