Antibacterial non-glycosidase activity of invertebrate destabilase-lysozyme and of its helical amphipathic peptides.

@article{Zavalova2006AntibacterialNA,
  title={Antibacterial non-glycosidase activity of invertebrate destabilase-lysozyme and of its helical amphipathic peptides.},
  author={L. L. Zavalova and Tatyana G Yudina and Irena I. Artamonova and Isolda P. Baskova},
  journal={Chemotherapy},
  year={2006},
  volume={52 3},
  pages={158-60}
}
BACKGROUND Since bactericidal properties of some lysozymes are independent of their glycosidase activity, we have investigated this phenomenon for destabilase-lysozyme (DL) from medicinal leech (Hirudo medicinalis). METHODS Glycosidase activity was determined on Micrococcus luteus, non-enzymatic antibacterial activity of heat-treated DL and of synthetic peptides alpha1, alpha2 and alpha3 (fragments of its primary structure) on M. luteus, Escherichia coli, Bacillus brevis and Streptomyces… CONTINUE READING

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