Antibacterial effect of naturally occurring unsaturated fatty acids from Prunus japonica against Propionibacterium acnes

  title={Antibacterial effect of naturally occurring unsaturated fatty acids from Prunus japonica against Propionibacterium acnes},
  author={Zakir Sultan and Ki-Moo Lee and S S Moon},
  journal={Oriental Pharmacy and Experimental Medicine},
SUMMARY The antibacterial activity-guided fractionation of the MeOH extract of seeds of traditionalmedicinal plant Prunus japonica resulted in the isolation of linoleic acid and cis-11-eicosenoicacids, and their methyl esters. Linoleic acid inhibited the growth of Propionibacterium acnes, theacne-causing anaerobic bacterium, but cis-11-eicosenoic acid, methyl linoleate, and cis-11-eicosenoate were found to be inactive. Together with isolated linoleic acid, authentic saturatedand unsaturated… 

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