Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro

  title={Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro},
  author={Outi Lepp{\"a}ranta and Minna Vaahtio and Timo Peltola and Di Zhang and Leena Hupa and Mikko Hupa and Heimo O. Yl{\"a}nen and Jukka I Salonen and Matti K. Viljanen and Erkki Eerola},
  journal={Journal of Materials Science: Materials in Medicine},
Bioactive glasses (BAGs) of different compositions have been studied for decades for clinical use and they have found many dental and orthopaedic applications. Particulate BAGs have also been shown to have antibacterial properties. This large-scale study shows that two bioactive glass powders (S53P4 and 13–93) and a sol–gel derived material (CaPSiO II) have an antibacterial effect on 17 clinically important anaerobic bacterial species. All the materials tested demonstrated growth inhibition… 

Antibacterial effect of bioactive glass nanoparticles prepared via sol gel method

These bioactive glass nanopowders can be regarded as good candidates in orthopedic application for the treatment of bone and dental defects but need supplementary and more evaluation considering their antibacterial effect on two important bacteria.

Antibacterial Properties of Bioactive Glasses

This chapter presents the available methods for the preparation of these materials, their application, type of bioactive glasses, factors that play a vital role in enhancing their antibacterial properties against various bacterial traits and a brief detail of techniques applied to carry out antibacterial studies of nanosizedBioactive glasses.

Recent Evidence on Bioactive Glass Antimicrobial and Antibiofilm Activity: A Mini-Review

The use of bioactive glass might be a promising solution for the reconstruction of bone defects, as well as for the treatment and eradication of bone infections, characterized by bone necrosis and destruction of the bone structure.

In vitro Study of the Antibacterial Activity of Bioactive Glass‐ceramic Scaffolds

This experimental study provides the first evidence in vitro that bioactive glass-ceramic scaffolds made from both 45S5 Bioglass and boron containingBioactive glass as well as their ionic dissolution products do no exhibit antibacterial effect against several strains of S. aureus.

S53P4 bioactive glass

Bioactive glasses and calcium phosphates

Comparison of antibacterial and antibiofilm activity of bioactive glass compounds S53P4 and 45S5

It is found that 45S5 seems to be as effective as S53P4 and possibly even more capable of limiting bacterial infections, and the efficacy of bioactive glass was not limited to inhibition of planktonic growth, as it also extended to bacterial biofilms.

Strontium-substituted bioactive glasses in vitro osteogenic and antibacterial effects.

Antibacterial effect of morphous (poly-crystalline) and amorphous (glass) nano-bioactive glass 45S5 on Streptococcus mutans

Streptococcus mutans (ATCC 35668) is not susceptible to poly-crystalline nanoBAG 45S5, and amorphous nano-BAG45S5 is bacteriostatic against Streptococcin mutans.



Bactericidal effects of bioactive glasses on clinically important aerobic bacteria

Bioactive glasses were found to clearly inhibit the growth of a wide selection of bacterial species causing e.g., infections on the surfaces of prostheses in the body after implantation.

Effect of Ion Release on Antibacterial Activity of Melt-Derived and Sol-Gel-Derived Reactive Ceramics

Four different bioreactive ceramics were prepared using a sol-gel method and a standard melting process. The aim was to study antibacterial effect of these materials on the growth of Staphylococcus

Factors Controlling Antibacterial Properties of Bioactive Glasses

Factors controlling the antibacterial ability of three bioactive glasses were studied by comparing the changes in the SBF during immersion of the glasses with their response to four microorganisms.

Broad-Spectrum Bactericidal Activity of Ag2O-Doped Bioactive Glass

An initial investigation of the in vitro antibacterial properties of AgBG, a novel bioactive glass composition doped with Ag2O, finds that it was bacteriostatic and bactericidal, but it also elicited a rapid bactericidal action.

Antibacterial and bioactive silver-containing Na2O·CaO·2SiO2 glass prepared by sol–gel method

High antimicrobial effects of samples against Escherichia coli and Streptococcus mutans were found and FTIR measurements and SEM micrographs have ascertained the formation of a hydroxyapatite layer on the surface of samples soaked in a simulated body fluid for different times.

In Vitro Attachment of Staphylococcus Epidermidis to Surgical Sutures with and without Ag-Containing Bioactive Glass Coating

This preliminary study has demonstrated the quantification and visualization of bacterial attachment onto sutures in order to compare the antibacterial properties of Ag-containing bioactive glass coatings.

Direct chemical bond of bioactive glass-ceramic materials to bone and muscle.

The objective of this research is to achieve direct chemical bonding of structurally strong implant materials with hard and soft tissues. This objective has been achieved through the development of a

The sintering range of porous bioactive glasses

The sintering properties of four established bioactive glasses and four novel glass compositions within the range of interest for bioactivity were studied. The sintering behaviour was evaluated using