Antibacterial constituents of three Cameroonian medicinal plants: Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensis

@article{Fouotsa2013AntibacterialCO,
  title={Antibacterial constituents of three Cameroonian medicinal plants: Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensis},
  author={Hugues Fouotsa and A. Mbaveng and C. D. Mbazoa and A. E. Nkengfack and S. Farzana and C. M. Iqbal and J. J. Marion Meyer and N. Lall and V. Kuete},
  journal={BMC Complementary and Alternative Medicine},
  year={2013},
  volume={13},
  pages={81 - 81}
}
BackgroundMultidrug resistance is a worrying cause of treatment failure in bacterial infections. The search of bioactive constituents from medicinal plants against multidrug resistant (MDR) bacteria has significantly evolved in the two last decades. In the present study, twenty-two compounds (three terpenoids, eleven phenolics and eight alkaloids) isolated from three Cameroonian medicinal plants, namely Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensis, as well as the crude… Expand
Antibacterial activities of the methanol extracts and compounds from Uapaca togoensis against Gram-negative multi-drug resistant phenotypes
TLDR
The present study demonstrates that U. togoensis can be explored more for the development of herbal drugs to tackle MDR bacterial infections. Expand
Isolation and Characterization of Antimycobacterial Compounds from Fruits of Aegle marmelos ( L . )
Root extracts of Aegle marmelos, an evergreen tree indigenous to India, is an important ingredient in Ayurvedic preparations used for the treatment of pulmonary tuberculosis. Leaves of the tree areExpand
Anti- toxoplasma gondii activity of constituents from Balsamocitrus camerunensis L (Rutaceae)
TLDR
Some of the isolated compounds showed noteworthy activity against Toxoplasma gondii intracellular parasite in mammals with an inhibition of parasite growth of around 46.44% for compounds 4 and 82.12% for compound 3 which was the most active compound. Expand
Anti-MRSA Constituents from Ruta chalepensis (Rutaceae) Grown in Iraq, and In Silico Studies on Two of Most Active Compounds, Chalepensin and 6-Hydroxy-rutin 3′,7-Dimethyl ether
TLDR
This is the first report on the anti-MRSA property of compounds isolated from R. chalepensis, and were active against four out of six tested MRSA strains, and in silico studies were performed on these compounds. Expand
In vitro assessment of antibiotic-resistance reversal of a methanol extract from Rosa canina L
TLDR
The crude methanol extract of Rosa canina fruit was tested against multidrug-resistant bacterial strains, including methicillin-resistant Staphylococcus aureus SA1199B, EMRSA16 and XU212 harbouring NorA, PBP2a and TetK resistance mechanisms, respectively, and the inhibition of bacterial plasmid conjugation opens the possibility of combination therapies to overcome antibiotic resistance. Expand
Potential Natural Antimycobacterial Metabolites from Some Sub-Saharan Medicinal Plants
TLDR
The biological activities of compounds derived from African medicinal plants with the potential for the treatment of anti-mycobacterial infections in sub-Sahara Africa covering the period from 1995 to 2013 are reported. Expand
ANTI-TUBERCULAR ACTIVITY OF EXTRACT AND COUMPOUNDS OF NONI (MORINDA CITRIFOLIA LINN)
Objective : This study aimed to evaluate the antitubercular activity of extracts and compounds isolated of Morinda citrofolia Linn (noni) against Mycobacterium tuberculosis strains (H37Rv) with aExpand
IN VITRO DPPH RADICAL SCAVENGING AND ANTI-BACTERIAL ACTIVITY OF OMAN'S CYMBOPOGON Short Communication
Objective: The objective of this work is to evaluate antioxidant and anti-microbial activity of methanolic extract of Omani Cymbopogan schoenanthus. Methods: Antibacterial activity of mehanolicExpand
Antibacterial and antibiofilm activities of polysaccharides, essential oil, and fatty oil extracted from Laurus nobilis growing in Lebanon.
TLDR
Alginate, fucoidan, fatty oils and essential oil have good antibacterial activities against the 5 bacterial strains, and a negligible biofilm eradication activity was observed, but a promising biofilm eradicate activity was obtained with alginates, which showed a reduced biofilm mass even at low concentration. Expand
Ethnobotany and the Role of Plant Natural Products in Antibiotic Drug Discovery.
TLDR
Key findings on the antibacterial potential of plant NPs are brought to the forefront for consideration in future antibiotic discovery and development efforts. Expand
...
1
2
3
...

References

SHOWING 1-10 OF 57 REFERENCES
Antibacterial Activities of Selected Cameroonian Plants and Their Synergistic Effects with Antibiotics against Bacteria Expressing MDR Phenotypes
TLDR
The results of this study suggest that the tested plant extracts and mostly those from P. nitida, G. lucida and G. kola could be used alone or in association with common antibiotics in the fight of bacterial infections involving MDR strains. Expand
Antimicrobial components of the methanolic extract from the stem bark of Garcinia smeathmannii Oliver (Clusiaceae)
TLDR
The overall results provide promising baseline information for the potential use of the crude extract from the stem bark of Garcinia smeathmannii as well as some of the isolated compounds in the treatment of bacterial and fungal infections. Expand
Antimicrobial activity of the methanolic extract and compounds from Teclea afzelii (Rutaceae)
TLDR
The overall results provide promising basis for the use of the crude extract as well as the isolated alkaloids in the treatment of specific microbial infections. Expand
Antimicrobial activity of the crude extracts and compounds from Ficus chlamydocarpa and Ficus cordata (Moraceae).
TLDR
Evidence is provided that the studied plants extract, as well as some of the isolated compounds might be potential sources of new antimicrobial drug. Expand
Bioassay-guided studies on the cytotoxic and in vitro trypanocidal activities of a sesquiterpene (Muzigadial) derived from a Ugandan medicinal plant (Warburgia ugandensis).
TLDR
It was concluded that the brine shrimp assay might be a useful predictor of trypanocidal activity of plant extracts and that muzigadial may be potentially valuable in the treatment of drug-resistant trypanosomosis. Expand
Potential of Cameroonian plants and derived products against microbial infections: a review.
  • V. Kuete
  • Biology, Medicine
  • Planta medica
  • 2010
TLDR
Many plant species are used in traditional medicine in Cameroon to treat infectious diseases, and several interesting openings have originated for further inquiry following IN VITRO antimicrobial activity evaluation. Expand
Cameroonian Medicinal Plants: Pharmacology and Derived Natural Products
TLDR
In conclusion, many medicinal plants traditionally used in Cameroon to treat various ailments displayed good activities in vitro, explaining the endeavor of Cameroonian research institutes in drug discovery from indigenous medicinal plants. Expand
Antimicrobial activity of the methanolic extracts and compounds from Treculia obovoidea (Moraceae).
TLDR
The obtained results provide promising baseline information for the potential use of these crude extract as well as some of the isolated compounds in the treatment of bacterial and fungal infections. Expand
Antibacterial, antifungal and antitubercular activity of (the roots of) Pelargonium reniforme (CURT) and Pelargonium sidoides (DC) (Geraniaceae) root extracts
TLDR
Acetone, chloroform and ethanol extracts of P. reniforme showed activity against M. tuberculosis exhibiting a minimum inhibitory concentration of 5 × 10 3 mg/L. Expand
ANTILISTERIAL POTENTIAL OF IMPERATORIN AND LIMONIN FROM PONCIRUS TRIFOLIATA RAFIN
To discover natural compounds with antilisterial potential, we investigated an ethyl acetate extract of the seeds of Poncirus trifoliata Rafin., and isolated imperatorin and limonin. The structuresExpand
...
1
2
3
4
5
...