Antibacterial and non-cytotoxic effect of nanocomposites based in polyethylene and copper nanoparticles.

Abstract

In this study, an antibacterial, but not cytotoxic nanomaterial based on polyethylene and copper nanoparticles was prepared by in situ polymerization. PE-CuNps nanocomposites against Escherichia coli, completely suppressed the number of live bacteria after 12 h incubation compared to neat PE. TEM images showed that nanocomposites damage the plasma membrane of the bacteria, revealing a bacteriolytic effect. Toxic effects of copper nanoparticles on viability of neuroblastoma line cell also was evaluated, revealing a non cytotoxic effect for the doses used, showing that this nanocomposite is a ideal material for medical devices.

DOI: 10.1007/s10856-015-5475-6

Cite this paper

@article{Tamayo2015AntibacterialAN, title={Antibacterial and non-cytotoxic effect of nanocomposites based in polyethylene and copper nanoparticles.}, author={Laura Tamayo and Paula A Zapata and Franco M Rabagliati and M Ignacio Az{\'o}car and Luis Alfredo Mu{\~n}oz and Xue-yun Zhou and George E. Thompson and Maritza P{\'a}ez}, journal={Journal of materials science. Materials in medicine}, year={2015}, volume={26 3}, pages={129} }