Antibacterial activity of the investigational oral and parenteral cephalosporin BK-218

  title={Antibacterial activity of the investigational oral and parenteral cephalosporin BK-218},
  author={D. M. Johnson and R. Jones},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  • D. M. Johnson, R. Jones
  • Published 2005
  • Biology, Medicine
  • European Journal of Clinical Microbiology and Infectious Diseases
BK-218 is a novel cephalosporin with a dual route of administration and spectrum of activity most similar to that of second-generation cephalosporins. BK-218 was active againstStreptococcus pneumoniae, Haemophilus influenzae andMoraxella catarrhalis but strains resistant to penicillins had higher MICs. BK-218 had greater activity (8-fold) than cefuroxime or cefaclor against oxacillin-susceptibleStaphylococcus spp. Moderate BK-218 activity was observed againstNeisseria gonorrhoeae and commonly… Expand
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