Antibacterial activity of multiple antigen peptides homologous to a loop region in human lactoferrin.

@article{Azuma1999AntibacterialAO,
  title={Antibacterial activity of multiple antigen peptides homologous to a loop region in human lactoferrin.},
  author={Masachika Azuma and Taiki Kojima and Itsuo Yokoyama and Hisao Tajiri and Kazumasa Yoshikawa and Shinsuke Saga and Carlos Adriel Del Carpio},
  journal={The journal of peptide research : official journal of the American Peptide Society},
  year={1999},
  volume={54 3},
  pages={237-41}
}
An 11-residue peptide (FQWQRNMRKVR) homologous to just over half the loop region of human lactoferricin is thought to be responsible for antimicrobial properties of human lactoferricin. Multiple antigen peptides (MAP) of the 11-residue peptide exerted significant antibacterial effects against a broad spectrum of bacteria including MRSA. More than eight branching was favourable for increasing its antibacterial activity. Our report shows a novel possibility for MAP to increase the activity of… CONTINUE READING