Antibacterial activity of liposome-entrapped ampicillin in vitro and in vivo in relation to the lipid composition.

Abstract

The antibacterial activity of liposome-entrapped ampicillin against Listeria monocytogenes was investigated in relation to the lipid composition of the liposomes. This was studied in vitro in mouse peritoneal macrophages infected with L. monocytogenes, as well as in vivo in experimental L. monocytogenes infection in mice. Two types of liposomes, a… (More)

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