Antibacterial activity of gold nanoparticles and their toxicity assessment

@article{Umamaheswari2014AntibacterialAO,
  title={Antibacterial activity of gold nanoparticles and their toxicity assessment},
  author={K Umamaheswari and Raju Baskar and K Rakesh Chandru and Nagappan Rajendiran and Shanmugam Chandirasekar},
  journal={BMC Infectious Diseases},
  year={2014},
  volume={14},
  pages={P64 - P64}
}
Methods The present study involved the synthesis of gold nanoparticles using a sodium cholate, as both reducing and capping agent and characterization by UVVisible spectroscopy and High ResolutionTransmission Electron Microscopy (HRTEM). The antibacterial activity on significant bacterial species was evaluated by micro broth dilution method. The mechanism for antibacterial action of the gold nanoparticles were studied by reactive oxygen species (ROS) generation that causes oxidative stress to… Expand
Antibacterial Efficacy of Gold and Silver Nanoparticles Functionalized with the Ubiquicidin (29–41) Antimicrobial Peptide
Recent studies have demonstrated that drug antimicrobial activity is enhanced when metallic nanoparticles are used as an inorganic support, obtaining synergic effects against microorganisms. TheExpand
Antibacterial and Anti-Biofilm Biosynthesised Silver and Gold Nanoparticles for Medical Applications: Mechanism of action, Toxicity and Current Status.
TLDR
In this review, the preparation of AgNPs and AuNPs using different methods is discussed, particularly the green or bio- synthesis method as well as common methods used for their physical and chemical characterization, along with the toxicity of both nanoparticles. Expand
Antibacterial effect of gold nanoparticles against Corynebacterium pseudotuberculosis
TLDR
Gold nanoparticles penetrated the thick wall of C. psudotuberculosis and accumulated as intracellular agglomerates and laser light enhanced the antimicrobial activity of gold nanoparticles by at least one fold due to its photo thermal combined effect. Expand
Sericin-functionalized GNPs potentiate the synergistic effect of levofloxacin and balofloxacin against MDR bacteria.
TLDR
The potential role of technologies based on gold nanoparticles (GNPs) has been evaluated and the antibacterial action of SrGNPs and their bioconjugated counterparts comprising Levo, Balo, and Levo/Balo were examined against normal and multi-drug resistant (MDR) strains of E. coli and S. aureus. Expand
Nanogold for In Vitro Inhibition of Salmonella Strains
The pathogenic strains of Salmonella typhi, paratyphi, and typhimurium are the major cause of typhoid and food poisoning in children and adults in developing countries. According to WHO estimation,Expand
A Review on Recent Trends in Green Synthesis of Gold Nanoparticles for Tuberculosis
TLDR
The main focus is on the role of the natural plant bio-molecules involved in the bioreduction of metal salts during the GNPs synthesis with phytoconstituents used as antitubercular agents. Expand
Nano-Strategies to Fight Multidrug Resistant Bacteria—“A Battle of the Titans”
TLDR
The use of nanoparticles still presents a challenge to therapy and much more research is needed in order to overcome this, so the current research on nanoparticles and other nanomaterials are summarized. Expand
Antibacterial Activity and Setting Time of Glass Ionomer Cement Modified by Nano Gold and Nano Silver
Nano-structured materials have been receiving considerable attention as a result of their unique physical, chemical, biological properties.
Impact of nanoparticles on human and environment: review of toxicity factors, exposures, control strategies, and future prospects
TLDR
The current status of toxicological studies dealing with nanoparticles, accomplishments, weaknesses, and future challenges are outlined and the strategies which can help to control human exposures to toxic nanoparticles are discussed. Expand