Antibacterial activity of curcumin (turmeric) against periopathogens - An in vitro evaluation

  title={Antibacterial activity of curcumin (turmeric) against periopathogens - An in vitro evaluation},
  author={Rasika Shyam Bomdyal and Mona Shah and Yogesh Doshi and Vidhi A. Shah and Supriya P. Khirade},
  journal={Journal of Advanced Clinical and Research Insights},
Periodontitis is an inflammation of supporting tissues of the teeth. It is usually a progressively destructive change, leading to loss of bone, periodontal ligament, and extension of inflammation from gingival to adjacent bone and ligament.[1] Periodontal diseases are referred to as inflammatory processes in periodontal tissues in response to the aggregation of bacteria on the teeth. The aggregation rarely leads to evident infection; however, the inflammatory response caused in the gingival… Expand
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Antibacterial Activity of Curcumin Against Periodontopathic Bacteria.
Curcumin possesses antibacterial activity against periodontopathic bacteria and may be a potent agent for preventing periodontal diseases. Expand
Novel therapeutic approach for the treatment of periodontitis by curcumin.
Locally delivered 1% curcumin gel was more effective in inhibiting the growth of oral bacteria when used as an adjunct to SRP in the treatment of chronic periodontitis. Expand
Efficacy of curcumin in the treatment of chronic gingivitis: a pilot study.
Curcumin is comparable to chlorhexidine as an anti-inflammatory mouthwash and can be considered as an effective adjunct to mechanical periodontal therapy. Expand
Generation of inflammatory stimuli: how bacteria set up inflammatory responses in the gingiva.
Bacterial components/virulence factors may be involved in modulating inflammatory responses and include: lipopolysaccharides, fimbriae, proteases, heat-shock proteins, formyl-methionyl peptides, and toxins. Expand
Traditional Medicinal Plant Extracts and Natural Products with Activity against Oral Bacteria: Potential Application in the Prevention and Treatment of Oral Diseases
  • E. Palombo
  • Medicine
  • Evidence-based complementary and alternative medicine : eCAM
  • 2011
Plant extracts or phytochemicals that inhibit the growth of oral pathogens, reduce the development of biofilms and dental plaque, influence the adhesion of bacteria to surfaces and reduce the symptoms of oral diseases will be discussed further. Expand
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S. mutans and L. acidophilus were susceptible to curcumin in the presence of blue light, however, due to light penetration and drug diffusion difficulties, these microorganisms within dentine carious lesions were less affected than they were in the biofilm phase. Expand
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The results suggest that mastic chewing gum is a useful antiplaque agent in reducing the bacterial growth in saliva and plaque formation on teeth. Expand