Antibacterial activity of aminals and hemiaminals of pyrazole and imidazole

@article{Lupsor2011AntibacterialAO,
  title={Antibacterial activity of aminals and hemiaminals of pyrazole and imidazole},
  author={Simona Lupsor and Florin Aonofriesei and Mircea Iovu},
  journal={Medicinal Chemistry Research},
  year={2011},
  volume={21},
  pages={3035-3042}
}
Antibacterial activity of 1,1′-methylenedipyrazole (AM1), 1-hydroxymethylpyrazole (SAM1), 1,1′-methylenediimidazole (AM2), and 1-hydroxymethylimidazole (SAM2) has been tested against reference and clinical strains by both difusimetric and broth dilution methods. Overall, the minimal inhibitory concentrations of tested compounds ranged from 180 to 270 μg/ml… CONTINUE READING