Antibacterial activity of 5-acylaminothiazole derivatives, synthetic drugs related to beta-lactam antibiotics.

@article{Pirotte1991AntibacterialAO,
  title={Antibacterial activity of 5-acylaminothiazole derivatives, synthetic drugs related to beta-lactam antibiotics.},
  author={Bernard Pirotte and Jacques Delarge and Jacques Coyette and Jean Marie Fr{\`e}re},
  journal={The Journal of antibiotics},
  year={1991},
  volume={44 8},
  pages={844-53}
}
Newly synthesized 5-acylaminothiazolium salts and one 5-acylaminothiazolidine, considering their chemical structure and reactivity, have been proposed as potential inhibitors of bacterial serine DD-peptidases. A moderate antibiotic activity with (5-phenylacetylamino-3-thiazolio)acetate and (5-phenylacetylaminothiazolidin-3-yl)acetic acid was observed on… CONTINUE READING