Antibacterial activity and mechanism of action of auranofin against multi-drug resistant bacterial pathogens


Traditional methods employed to discover new antibiotics are both a time-consuming and financially-taxing venture. This has led researchers to mine existing libraries of clinical molecules in order to repurpose old drugs for new applications (as antimicrobials). Such an effort led to the discovery of auranofin, a drug initially approved as an anti-rheumatic… (More)
DOI: 10.1038/srep22571