Antibacterial activity and cytotoxicity analysis of halistanol trisulphate from marine sponge Petromica citrina.

@article{Marinho2012AntibacterialAA,
  title={Antibacterial activity and cytotoxicity analysis of halistanol trisulphate from marine sponge Petromica citrina.},
  author={Palloma Rodrigues Marinho and Naomi Kato Simas and Ricardo Machado Kuster and Rafael Silva Duarte and S{\'e}rgio Eduardo Longo Fracalanzza and Davis Fernandes Ferreira and Maria Teresa Villela Romanos and Guilherme Muricy and Marcia Giambiagi-deMarval and Marinella Silva Laport},
  journal={The Journal of antimicrobial chemotherapy},
  year={2012},
  volume={67 10},
  pages={
          2396-400
        }
}
OBJECTIVES An aqueous extract and fraction from the marine sponge Petromica citrina have antibacterial activity. We performed a chemical and biological characterization of the antibiotic substance from P. citrina and investigated its mode of action on Staphylococcus aureus cells. METHODS The inhibitory activity of the aqueous extract of P. citrina was determined against 14 bacteria belonging to type strains and clinical antibiotic-resistant strains. The aqueous extract was fractionated under… 
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References

SHOWING 1-10 OF 27 REFERENCES

Antibiotic-resistant bacteria inhibited by extracts and fractions from Brazilian marine sponges

In vitro screening of marine sponges in the search for novel substances against antibiotic- resistant bacteria demonstrated for the first time that P. citrina is a potential source of new drugs for the treatment of infections by antibiotic-resistant bacteria.

Antimicrobial activity of marine sponges against coagulase-negative staphylococci isolated from bovine mastitis.

Marine sponges: potential sources of new antimicrobial drugs.

The discoveries of products derived from marine sponges and associated bacteria that have shown in vivo efficacy or potent in vitro activity against infectious and parasitic diseases, including bacterial, viral, fungal and protozoan infections are surveyed.

Antifungal tests in phytochemical investigations: comparison of bioautographic methods using phytopathogenic and human pathogenic fungi.

Most of the plant-derived compounds tested showed a positive response in both assays, but with detection limits varying by a factor up to tenfold, it is thus advisable to use both tests, as some activities would otherwise go undetected.

Isolamento e atividades biológicas de produtos naturais das esponjas Monanchora arbuscula , Aplysina sp., Petromica ciocalyptoides e Topsentia ophiraphidites , da ascídia Didemnum ligulum e do octocoral Carijoa riisei

The investigation of extracts from six species of marine invertebrates yielded one new and several known natural products, including the new N,N-dimethyl-O-methylethanolamine, which displayed cytotoxic activity against the cancer cell lines SF295, MDA-MB435, HCT8 and HL60.

Anti-inflammatory activity of ethylacetate fraction of Cliona celata

It is shown for the first time that ECC inhibits NF-κB activation through the inhibition of IκB degradation, and regulates the expression of inducible nitric oxide synthase in lipopolysaccharide-stimulated murine macrophage-like RAW264.7 cells.

Microbial surfactants of marine origin: potentials and prospects.

Surfactant and emulsifier molecules having diverse chemical nature, including glycolipids and lipopeptides, have tremendous potential to be used in industrial processes, for environmental remediation and as drugs.

Susceptibility of Brazilian staphylococcal strains to glycopeptides evaluated by different testing methods.

All the staphylococci were susceptible to vancomycin by the disk diffusion test (DDT), but two CNS isolates presented intermediate resistance to teicoplanin by the DDT and MICs of susceptibility, with two other CNS strains, teic planetin-susceptible by theDDT, presented MIC's of intermediate resistance.

Susceptibility of Brazilian Staphylococcal Strains to Glycopeptides Evaluated by Different Testing Methods

All the staphylococci were susceptible to vancomycin by the disk diffusion test (DDT), but two CNS isolates presented intermediate resistance to teicoplanin by the DDT and MICs of susceptibility, with two other CNS strains, teioplanin-susceptible by theDDT, presented MIC's of intermediate resistance.

Molecular Characterization of Quinolone-Resistant Neisseria gonorrhoeae Isolates from Brazil

The results indicate that fluoroquinolones may no longer be used as first line antibiotics for the treatment of gonorrhea in Rio de Janeiro, and that programs for antimicrobial susceptibility surveillance of N. gonorrhoeae should also be implemented in other regions of Brazil.