Antiatherogenic effect of Pistacia lentiscus via GSH restoration and downregulation of CD36 mRNA expression.

@article{Dedoussis2004AntiatherogenicEO,
  title={Antiatherogenic effect of Pistacia lentiscus via GSH restoration and downregulation of CD36 mRNA expression.},
  author={George V Z Dedoussis and Andriana C Kaliora and Spyridon Psarras and Antonia Chiou and Anastasia Mylona and Nikolaos Papadopoulos and Nikolaos K. Andrikopoulos},
  journal={Atherosclerosis},
  year={2004},
  volume={174 2},
  pages={
          293-303
        }
}
Pistacia lentiscus var. Chia (Anacardiaceae) grows almost exclusively on Chios Island, Greece, and gives a resinous exudate resin used for culinary purposes by Mediterranean people. We investigated the molecular mechanisms through which total polar extract of the resin inhibits oxidized low-density lipoprotein (oxLDL) cytotoxic effect on peripheral blood mononuclear cell (PBMC). Cells exposed to oxLDL underwent apoptosis and necrosis, dependent on the duration of exposure. When culturing cells… CONTINUE READING

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