Corpus ID: 55016832

Antiasthmatic Effect of Eugenol (4-Allyl-2-Methoxyophenol) Mediated by Both Bronchodilator and Immunomodulatory Properties

@inproceedings{Campos2014AntiasthmaticEO,
  title={Antiasthmatic Effect of Eugenol (4-Allyl-2-Methoxyophenol) Mediated by Both Bronchodilator and Immunomodulatory Properties},
  author={Keina Maciele Campos and Tatiane O. Teixeira and Ana Tereza Cerqueira Lima and Ryan S Costa and Tamires Cana Brasil Carneiro and Darizy Fl{\'a}via Silva and Maur{\'i}cio Lima Barreto and Lain Pontes-de-carvalho and Neuza Maria Neves Alcantara and Camila Alexandrina Figueiredo},
  year={2014}
}
Eugenol, an aromatic product, exhibits anti-inflammatory properties, however, little is known about its effect in allergic inflammation mediated by Th2-type cells and cytokines. We examined the pharmacological potential of this compound in a murine model of respiratory allergy to Bt (Blomia tropicalis). For this, AJ mice were sensitized (100 µg/animal s.c.) and challenged (10 μg/animal i.n.) with Bt mite extract. Sensitized animals were treated or not with eugenol (20, 40 or 80 mg/kg) and the… Expand
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