Antiarthritic Potential of Comprehensively Standardized Extract of Alternanthera bettzickiana: In Vitro and In Vivo Studies

@article{Manan2020AntiarthriticPO,
  title={Antiarthritic Potential of Comprehensively Standardized Extract of Alternanthera bettzickiana: In Vitro and In Vivo Studies},
  author={Maria Manan and Uzma Saleem and Muhammad Sajid Hamid Akash and Muhammad Qasim and Muhammad Hayat and Zohaib Raza and Bashir Ahmad},
  journal={ACS Omega},
  year={2020},
  volume={5},
  pages={19478 - 19496}
}
Alternanthera bettzickiana is being used as a folk remedy for treating arthritis by conventional healers in Thailand. The current research was undertaken to explore the antiarthritic potential of A. bettzickiana ethanolic extract (ABEE). Plant characterization, molecular docking, and in vitro and in vivo (ABEE at 250, 500, and 1000 mg/kg was administered orally to rats once daily for 28 days) studies to explore the antiarthritic effect and enzyme-linked immunosorbent assay (ELISA) and real-time… 
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The outcomes of the study proposed that S. saligna have anti-arthritic potential, supporting its traditional use for rheumatoid arthritis treatment.
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MRJPs significantly ameliorated NAFLD induced by a high-fat diet in mice, suggesting that MRJPs could be used as an active ingredient to help improveNAFLD, which was beneficial for the development of related functional foods and the economic value of RJ.
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