Antiarrhythmic efficacy of N-acetylprocainamide in patients with premature ventricular contractions.

Abstract

Oral administration of a 1.5-gm dose of N-acetylprocainamide (NAPA) to 9 patients with premature ventricular contractions (PVCs) confirmed previous indirect evidence that this metabolite of procainamide has antiarrhythmic efficacy and potency comparable to those of procainamide. Although the mechanism by which NAPA acts as an antiarrhythmic drug is not… (More)

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@article{Lee1976AntiarrhythmicEO, title={Antiarrhythmic efficacy of N-acetylprocainamide in patients with premature ventricular contractions.}, author={W. K. Lee and Jennifer Strong and Raymond Kehoe and Julie Dutcher and Amanda Atkinson}, journal={Clinical pharmacology and therapeutics}, year={1976}, volume={19 5 Pt 1}, pages={508-14} }