Antiarrhythmic effects of the angiotensin converting enzyme inhibitor perindoprilat in a pig model of acute regional myocardial ischemia.

Abstract

Previous studies on the possible antiarrhythmic effects of angiotensin converting enzyme (ACE) inhibitors during early ischemia in pigs have been inconclusive or negative; however, proof of adequate ACE inhibition was not provided. Perindoprilat, 0.06 mg/kg, i.v., was administered 30 min prior to ligation of the anterior descending coronary artery (CAL) in… (More)

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@article{Muller1992AntiarrhythmicEO, title={Antiarrhythmic effects of the angiotensin converting enzyme inhibitor perindoprilat in a pig model of acute regional myocardial ischemia.}, author={Cecilia A. Muller and Lionel Henry Opie and Max Peisach and Carlos A. Pineda}, journal={Journal of cardiovascular pharmacology}, year={1992}, volume={19 5}, pages={748-54} }