Antiarrhythmic and electrophysiological effects of long-chain omega-3 polyunsaturated fatty acids.

@article{Dhein2005AntiarrhythmicAE,
  title={Antiarrhythmic and electrophysiological effects of long-chain omega-3 polyunsaturated fatty acids.},
  author={Stefan Dhein and B. J. De Michaelis and F E Mohr},
  journal={Naunyn-Schmiedeberg's archives of pharmacology},
  year={2005},
  volume={371 3},
  pages={202-11}
}
Recent studies indicate that a diet enriched in omega-3 polyunsaturated fatty acids may prevent sudden cardiac death. The goal of the present study was to elucidate how omega-3 polyunsaturated fatty acids such as docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and alpha-linolenic acid (ALA; 1-20 microM) may affect the cardiac activation and repolarization pattern. For this reason, DHA, EPA or ALA was infused in spontaneously beating isolated rabbit heart (Langendorff technique) and… CONTINUE READING