Antiangiogenics: the potential role of integrating this novel treatment modality with chemoradiation for solid cancers.

@article{Duda2007AntiangiogenicsTP,
  title={Antiangiogenics: the potential role of integrating this novel treatment modality with chemoradiation for solid cancers.},
  author={Dan G Duda and Rakesh K. Jain and Christopher G Willett},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2007},
  volume={25 26},
  pages={4033-42}
}
Although still in very early stages of clinical development, the combination of antiangiogenics with contemporary chemoradiotherapy regimens has emerged as a feasible and promising approach to many cancers. We review the rationale and the current understanding of antiangiogenics and their therapeutic potential in combination with chemoradiotherapy. Finally, we offer a perspective on future research directions aimed at making this complex therapeutic approach successful in the clinic. 

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