Antiangiogenic therapy in hematologic malignancies.

  title={Antiangiogenic therapy in hematologic malignancies.},
  author={Thomas M. Moehler and Jens Hillenga\ss and Hartmut Goldschmidt and Anthony D. Ho},
  journal={Current pharmaceutical design},
  volume={10 11},
Angiogenesis is defined as the formation of new capillaries from prexisting blood vessels and plays an important role in the progression of solid tumors and hematologic malignancies. Markers of angiogenesis correlate with clinical characteristics in leukemia and non-Hodgkin's-lymphoma, serving as predictors of poor prognosis. Antiangiogenic effects of… CONTINUE READING