Antiangiogenic effects of topically administered multiple kinase inhibitor, motesanib (AMG 706), on experimental choroidal neovascularization in mice.

Abstract

PURPOSE To investigate the effect of topical motesanib, an inhibitor of receptor tyrosine kinase, on experimental choroidal neovascularization (CNV). METHODS CNV was induced in 46 nine-week-old male C57BL/6 mice using fundus laser photocoagulation. The right eye of each mouse was treated with motesanib eye drop (4 times daily) and the left eye with… (More)
DOI: 10.1089/jop.2014.0023

Cite this paper

@article{Rho2015AntiangiogenicEO, title={Antiangiogenic effects of topically administered multiple kinase inhibitor, motesanib (AMG 706), on experimental choroidal neovascularization in mice.}, author={Chang Rae Rho and Seungbum Kang and Ki Cheol Park and K Yang and HyunSu Choi and Won-Kyung Cho}, journal={Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics}, year={2015}, volume={31 1}, pages={25-31} }