Antiangiogenic VEGF Isoform in Inflammatory Myopathies

@inproceedings{Volpi2013AntiangiogenicVI,
  title={Antiangiogenic VEGF Isoform in Inflammatory Myopathies},
  author={Nila Volpi and Alessandra Pecorelli and Paola Lorenzoni and Francesco Di Lazzaro and G. De Piero Belmonte and Margherita Aglian{\'o} and Luca Cantarini and Fabio Giovanni Giannini and Giovanni Grasso and Giuseppe Valacchi},
  booktitle={Mediators of inflammation},
  year={2013}
}
OBJECTIVE To investigate expression of vascular endothelial growth factor (VEGF) antiangiogenic isoform A-165b on human muscle in idiopathic inflammatory myopathies (IIM) and to compare distribution of angiogenic/antiangiogenic VEGFs, as isoforms shifts are described in other autoimmune disorders. SUBJECTS AND METHODS We analyzed VEGF-A165b and VEGF-A by western blot and immunohistochemistry on skeletal muscle biopsies from 21 patients affected with IIM (polymyositis, dermatomyositis, and… CONTINUE READING

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