Antiangiogenesis treatment combined with chemotherapy produces chondrosarcoma necrosis.

@article{Morioka2003AntiangiogenesisTC,
  title={Antiangiogenesis treatment combined with chemotherapy produces chondrosarcoma necrosis.},
  author={Hideo Morioka and Lawrence Weissbach and Tikva Vogel and G. Petur Nielsen and Glynn T. Faircloth and Li Shao and Francis Hornicek},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2003},
  volume={9 3},
  pages={1211-7}
}
A combination therapy protocol using a marine chemotherapeutic and an antiangiogenic molecule was tested in a mouse tumor xenograft model for the ability to curtail the growth of a human chondrosarcoma (CHSA). Ecteinascidin-743 (ET-743), a marine-derived chemotherapeutic, was effective at slowing the growth of a primary CHSA. Plasminogen-related protein B… CONTINUE READING