Antiangiogenesis drug design: multiple pathways targeting tumor vasculature.

@article{Zhong2006AntiangiogenesisDD,
  title={Antiangiogenesis drug design: multiple pathways targeting tumor vasculature.},
  author={Haizhen Andy Zhong and J. Phillip Bowen},
  journal={Current medicinal chemistry},
  year={2006},
  volume={13 8},
  pages={
          849-62
        }
}
The initiation, growth, and development of new blood vessels through angiogenesis are essential for tumor growth. Tumor masses require access to blood vessels for a sufficient supply of oxygen and nutrients to maintain growth and metastasis. Inhibiting tumor blood vessel formation as proposed by Judah Folkman in the early 1970s, therefore, offers promising therapeutic approaches for treating tumor afflicted patients. The blood vessel growth in normal tissues is regulated though a delicate and… CONTINUE READING

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