Antianginal efficacy of carvedilol, a new beta-blocker with vasodilating action.

  title={Antianginal efficacy of carvedilol, a new beta-blocker with vasodilating action.},
  author={Salim Jamal and Saul Ben Freedman and Allen Thomson and Gwendolyn S Carter and Phillip J. Harris and David T. Kelly},
  journal={Journal of cardiovascular pharmacology},
  volume={10 Suppl 11},
To evaluate the antianginal efficacy of carvedilol, a beta-blocker with vasodilating activity, we performed a randomized double-blind placebo-controlled study of two single doses of carvedilol. Twelve patients (eight males, four females, mean age 57 years) with stable effort angina and a positive exercise ECG with angina underwent treadmill exercise testing 2 h after either placebo, or carvedilol 25 or 50 mg. Both doses of carvedilol reduced resting heart rate but only the 50 mg dose reduced… CONTINUE READING

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