Antiamoebins, myrocin B and the basis of antifungal antibiosis in the coprophilous fungus Stilbella erythrocephala (syn. S. fimetaria).

@article{Lehr2006AntiamoebinsMB,
  title={Antiamoebins, myrocin B and the basis of antifungal antibiosis in the coprophilous fungus Stilbella erythrocephala (syn. S. fimetaria).},
  author={Nina A. Lehr and A. Meffert and L. Antelo and O. Sterner and H. Anke and R. Weber},
  journal={FEMS microbiology ecology},
  year={2006},
  volume={55 1},
  pages={
          105-12
        }
}
Antiamoebins I, III and XVI as well as several others in minor amounts were produced by four strains of the coprophilous fungus Stilbella erythrocephala (syn. S. fimetaria) in its natural substrate and in liquid culture. The total antiamoebin concentration in dung was 126-624 microg g(-1) fresh weight, with minimum inhibitory concentrations against most other coprophilous fungi being at or below 100 microg mL(-1). Myrocin B, not previously described from S. erythrocephala, was also produced… Expand
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References

SHOWING 1-10 OF 30 REFERENCES
Production of sordarin and related metabolites by the coprophilous fungus Podospora pleiospora in submerged culture and in its natural substrate.
TLDR
Sordarin-type natural products are synthesized by P. pleiospora at sufficiently high concentrations to account for antibiosis against yeasts, but not against filamentous fungi. Expand
Antagonism between stilbella erythrocephala and other coprophilous fungi
Stilbella erythrocephala, a common fungus on rabbit dung, produces a diffusible antibiotic in culture which causes significant inhibition of growth of many other coprophilous fungi, some fungalExpand
3-hydroxypropionic acid as a nematicidal principle in endophytic fungi.
3- Hydroxypropionic acid was isolated by bioactivity-guided fractionation of extracts obtained from submerged cultures of several endophytic fungi isolated from above-ground plant organs. ThisExpand
Production of Antibiotics by Collybia nivalis, Omphalotus olearius, a Favolaschia and a Pterula Species on Natural Substrates
TLDR
Collybia nivalis was found to be the first species of this genus to produce strobilurins and oudemansin A, and the concentrations of the antibiotics were sufficient to inhibit other saprophytic fungi. Expand
New sequences and new fungal producers of peptaibol antibiotics antiamoebins
  • A. Jaworski, H. Brückner
  • Chemistry, Medicine
  • Journal of peptide science : an official publication of the European Peptide Society
  • 2000
TLDR
Mixtures of the microheterogeneous 16‐mer peptaibol antibiotics called antiamoebins (AAM) have been isolated from the culture broths of strains of the filamentous fungi and some characteristic features are recognized in the mass spectrometric fragmentation pattern. Expand
New peptaibols from Mycogone cervina.
TLDR
From cultures of Mycogone cervina, a mycophilic fungus growing on the fruit bodies of ascomycete Paxina acetabulum, two new peptaibols (cervinin and the red-Leu O-acetylated derivative 2) were isolated and exhibited weak antibacterial and cytotoxic activities. Expand
Assays of the biological activities of guaiane sesquiterpenoids isolated from the fruit bodies of edible lactarius species.
  • H. Anke, O. Bergendorff, O. Sterner
  • Biology, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1989
TLDR
Three sesquiterpenoids that are found in the edible mushrooms Lactarius deliciosus, L. deterrimus and L. sanguifluus, have been assayed for biological activity and all three compounds showed weak mutagenic activity in the Ames assay. Expand
Cell wall synthesis is a major target of mycoparasitic antagonism by Trichoderma harzianum
TLDR
Cell wall turnover is identified as a major target of mycoparasitic antagonism because of an inhibition of the membrane-bound beta-1,3-glucan synthase of the host by the peptaibols, which inhibit the resynthesis of cell wall beta- glucans, sustain the disruptive action of beta-Glucanases, and all together enhance the fungicidal activity. Expand
Trichorzins HA and MA, antibiotic peptides from Trichoderma harzianum. I. Fermentation, isolation and biological properties.
TLDR
Trichorzins HA and MA, original 18-residue peptides, were isolated from two strains of the widespread soil fungus Trichoderma harzianum which have been shown to exhibit antibiotic activity against phytopathogenic fungi and structure-activity relationships were deduced from the antibiotic and membrane-modifying properties. Expand
Parallel formation and synergism of hydrolytic enzymes and peptaibol antibiotics, molecular mechanisms involved in the antagonistic action of Trichoderma harzianum against phytopathogenic fungi
TLDR
When the enzymes and the peptaibols were tested together, an antifungal synergistic interaction was observed and the 50% effective dose values obtained were in the range of those determined in the culture supernatants. Expand
...
1
2
3
...