Antiamnesic Effect of B. monniera on L-NNA Induced Amnesia Involves Calmodulin

  title={Antiamnesic Effect of B. monniera on L-NNA Induced Amnesia Involves Calmodulin},
  author={Akshay Anand and Manish Kumar Saraf and Sudesh S. Prabhakar},
  journal={Neurochemical Research},
Amnesia may result from ageing, chronic drug abuse or head injury and there are limited therapeutic strategies to such conditions. We have shown that Bacopa monniera, a memory enhancing drug can reverse both diazepam and scopolamine induced amnesia in mice. In order to understand the downstream effects of B. monniera, this study was designed to investigate how B. monniera antagonizes MK801, an NMDA receptor antagonist and N ω-Nitro-L-arginine (L-NNA), a nitric oxide synthase inhibitor. We… CONTINUE READING


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