Anti-tumour activity of heat-shock protein 60-recognizing CD4+ T cells against syngeneic murine renal cell carcinoma.

@article{Eto2005AntitumourAO,
  title={Anti-tumour activity of heat-shock protein 60-recognizing CD4+ T cells against syngeneic murine renal cell carcinoma.},
  author={Masatoshi Eto and Mamoru Harada and Katsunori Tatsugami and Masahiko Harano and Hirofumi Koga and Goro Matsuzaki and Seiji Naito},
  journal={BJU international},
  year={2005},
  volume={95 3},
  pages={421-4}
}
OBJECTIVES To determine whether heat-shock protein (HSP) 60-recognizing CD4(+) T cells show antitumour activity against renal carcinoma (RENCA) cells, as HSP is highly expressed by tumour cells and induced in cells by various stresses, including transformation. MATERIALS AND METHODS RENCA, a renal cortical adenocarcinoma cell line of BALB/c origin, was… CONTINUE READING