Anti-tumor immunity in B-lymphocyte-deprived mice. III. Immunity to primary Moloney sarcoma virus-induced tumors.

@article{Gordon1982AntitumorII,
  title={Anti-tumor immunity in B-lymphocyte-deprived mice. III. Immunity to primary Moloney sarcoma virus-induced tumors.},
  author={John Howard Gordon and Howard Thomas Holden and Shraga Segal and Michael S. Feldman},
  journal={International journal of cancer},
  year={1982},
  volume={29 3},
  pages={
          351-7
        }
}
Tumor induction and immunity to tumors were studied following the injection of Moloney sarcoma virus (MSV) into mice whose B-lymphocyte functions had been suppressed by the chronic administration of anti-IgM antibodies. Two preparations of MSV were used; one which gives rise to tumors which uniformly regress in normal adult mice, and another which elicits progressively growing tumors in the majority of recipients. The tumor incidence, mean tumor size, and tempo of regression were not modified… CONTINUE READING
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