Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis.

@article{Liu2013AntitumorEO,
  title={Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis.},
  author={Yunyi Liu and Wei Wang and Bin Fang and Fengyun Ma and Qian Zheng and Pengyi Deng and Shasha Zhao and Mingjie Chen and Guangxiao Yang and Guangyuan He},
  journal={European journal of pharmacology},
  year={2013},
  volume={698 1-3},
  pages={95-102}
}
Germacrone is one of the main bioactive components in the traditional Chinese medicine Rhizoma curcuma. In this study, the anti-proliferative effect of germacrone on the human hepatoma cell lines and the molecular mechanism underlying the cytotoxicity of germacrone were investigated. Treatment of human hepatoma cell lines HepG2 and Bel7402 with germacrone… CONTINUE READING