Anti-tumor and immunomodulating activities of proteoglycans from mycelium of Phellinus nigricans and culture medium.


Two proteoglycans, PNW1 and PNM1, were isolated from the mycelium of Phellinus nigricans through submerged fermentation and culture medium, respectively. PNW1 and PNM1 with similar average molecular weight (33 kDa and 29 kDa) were composed of glucose, galactose, mannose, arabinose and fucose in the molar ratios of 3.26:8.77:6.44:1:1.35 and 20.06:8.72:6.94:1… (More)
DOI: 10.1016/j.intimp.2008.02.008

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