Anti-stress effects of 20(S)-protopanaxadiol and 20(S)-protopanaxatriol in immobilized mice.

@article{Oh2015AntistressEO,
  title={Anti-stress effects of 20(S)-protopanaxadiol and 20(S)-protopanaxatriol in immobilized mice.},
  author={Hyun Ah Oh and Dae-Eung Kim and Hyuck Jai Choi and Nam Jae Kim and Dong-Hyun Kim},
  journal={Biological & pharmaceutical bulletin},
  year={2015},
  volume={38 2},
  pages={331-5}
}
Panax ginseng C.A. MEYER (Araliaceae), which contains ginsenosides as its main components, has been shown to have various biological effects, including anti-inflammatory, anxiolytic, anti-stress, and anti-tumor effects. Orally administered ginsenoside Rb1 and Re are metabolized to 20(S)-protopanaxadiol (PPD) and compound K via ginsenoside Rd and 20(S)-protopanaxatriol (PPT) and ginsenoside Rh1 via ginsenoside Rg1 by gut microbiota, respectively. Therefore, we investigated the anti-stress… CONTINUE READING
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