Anti-stress and nootropic activity of drugs affecting the renin-angiotensin system in rats based on indirect biochemical evidence.

@article{Kumar2015AntistressAN,
  title={Anti-stress and nootropic activity of drugs affecting the renin-angiotensin system in rats based on indirect biochemical evidence.},
  author={K V Anil Kumar and Shrasti Nagwar and Rama Thyloor and Sreemantula Satyanarayana},
  journal={Journal of the renin-angiotensin-aldosterone system : JRAAS},
  year={2015},
  volume={16 4},
  pages={801-12}
}
INTRODUCTION Various stress hormones are responsible for bringing out stress-related changes and are implicated in learning and memory processes. The extensive clinical experience of angiotensin receptor blockers (ARBs) and direct renin inhibitor as antihypertensive agents provides anecdotal evidence of improvements in cognition. The neurochemical basis underlying the anti-stress and nootropic effects are unclear. This study was aimed to determine the effects of aliskiren, valsartan and their… CONTINUE READING
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